Glioblastoma

A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Also Known As:

Glioblastoma Multiforme; Grade IV Astrocytoma; Astrocytomas, Grade IV; Giant Cell Glioblastomas; Glioblastoma, Giant Cell; Glioblastomas; Glioblastomas, Giant Cell; Grade IV Astrocytomas; Astrocytoma, Grade IV; Giant Cell Glioblastoma

Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroepithelial Neoplasms: 412
        Glioma: 42261
        Astrocytoma: 7343
        Glioblastoma: 28707
  - Glandular and Epithelial Neoplasms: 439
    - Neuroepithelial Neoplasms: 412
      - Glioma: 42261
        Astrocytoma: 7343
        Glioblastoma: 28707
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroepithelial Neoplasms: 412
        Glioma: 42261
        Astrocytoma: 7343
        Glioblastoma: 28707

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Disease

Drug/Important Bio-Agent (IBA)